The Dative Alternation in English

In English, there is a dative lexical alternation between a prepositional dative (PD) and a double object dative (DOD): I gnoe a book to lohn alternates with I gaae lohn a book. However, the dative alternation in English is more complex than this appears. There are three dative lexical structures and two alternations with four different types of constraints on how productive the DOD is. Fourteen different verb classes are affected by these constraints, leading to a complex picture that is verb dependent. In this paper I will discuss the syntactic and semantic characteristics of the alternation, the constraints and dative verb classes, and finally, the issue of markedness. It is important for language practitioners and acquisition researchers to understand the complexity of this alternation and the learnability issue. Acquisition of the dative alternation is not merely the acquisition of alternative syntactic structures, but the acquisition of the lexical characteristics of individual verbs, which is a far more complex task

Case-Building Behavior, Persistence, and Emergence Success of \u3ci\u3ePycnopsyche Guttifer\u3c/i\u3e (Walker) (Trichoptera: Limnephilidae) in Laboratory and \u3ci\u3ein situ\u3c/i\u3e Environments: Potential Trade-Offs of Material Preference

When removed from their cases in a non-flow laboratory environment, 5th instar Pycnopsyche guttifer (Walker) larvae were always successful in constructing a new case within 24 h when woody debris was present as a material choice. Most were successful within 1 h. Larvae were never successful at case building in the absence of wood in a non-flow environment. These laboratory-constructed ‘emergency cases’ were flimsy, lacking in shape, and larger than field cases. Laboratory case size, shape, and material preference remained constant after repeated daily evacuations over a series of 10 days. Larvae could be induced to construct a case composed of mineral particles only in the absence of wood and when placed in a laboratory stream with simulated flow conditions, or in situ in a natural stream. The emergence success of P. guttifer specimens induced to build these mineral cases, however, was significantly higher than that of larvae remaining in their field cases or of larvae that built wood cases. This result is likely due to a fungal infection that affected only larvae in wood cases. Our results demonstrate a scenario where a clearly non-preferred case construction material appears to increase survival

My preferred pronoun is she: Understanding transgender identity and oral health care needs

This literature review summarizes current research and evidence regarding transgender persons and oral health. Methods: A search of the literature was conducted in the following databases: PubMed, Google Scholar, EBSCO Host, Science Direct, and Wiley Online Library using the keywords transgender identity, gender non-conforming, discrimination, transition, binary systems, transgender oral cavity, transgender, transgender oral health, transgender dental health. Articles published from 2000 to 2017 in both peer-reviewed and non-peer reviewed journals, which reported information regarding the oral health status of transgender populations, were selected for review. Results: The search revealed 18 articles, only 7 of which pertained to the oral health status of transgender client populations. Five other articles were eliminated due to either poor quality or irrelevance. Discussion: The 13 articles included in the review revealed a need for oral health care professionals to be aware that gender is not binary, nor is it a mental health disorder. Transgender people face heightened risk of discrimination, violence, anxiety, depression, suicidality, substance abuse, and sexually transmitted diseases, as well as significant barriers to health care of which oral health professionals should be made aware. Conclusions: Transgender people have the same rights as everyone else to oral health care. Oral health care providers are responsible for ensuring that transgender clients receive care that aligns with their needs and for providing that care in a culturally competent manner. This requires an understanding of the basics of gender nonconformance and its impact on oral-systemic health. Additional research is needed to increase the scientific knowledge base to facilitate improved health outcomes for this client population

Child survival in England: Strengthening governance for health.

The United Kingdom, like all European countries, is struggling to strengthen health systems and improve conditions for child health and survival. Child mortality in the UK has failed to improve in line with other countries. Securing optimal conditions for child health requires a healthy society, strong health system, and effective health care. We examine inter-sectoral and intra-sectoral policy and governance for child health and survival in England. Literature reviews and universally applicable clinical scenarios were used to examine child health problems and English policy and governance responses for improving child health through integrating care and strengthening health systems, over the past 15 years. We applied the TAPIC framework for analysing policy governance: transparency, accountability, participation, integrity, and capacity. We identified strengths and weaknesses in child health governance in all the five domains. However there remain policy failures that are not fully explained by the TAPIC framework. Other problems with successfully translating policy to improved health that we identified include policy flux; policies insufficiently supported by delivery mechanisms, measurable targets, and sufficient budgets; and policies with unintended or contradictory aspects. We make recommendations for inter-sectoral and intra-sectoral child health governance, policy, and action to improve child health in England with relevant lessons for other countries

Copy number variation in co-morbid neurodevelopmental disorders

Copy number variants (CNVs) have been implicated in the pathogenesis of clinically distinct neurodevelopmental disorders (NDDs), indicating common underlying pathophysiology. Yet, the frequency, genetic architecture, and phenotypic role of pathogenic CNVs in adults with co-morbid neurodevelopmental phenotypes has not yet been systematically investigated. Adults with intellectual disability (ID) and psychiatric co-morbidities were recruited from ID psychiatry services across the UK (N=202). Using a genotype-first approach, chromosomal microarray analysis (CMA) was undertaken, and variants were categorised using the NHS regional genetics service (RGCs) clinical pipeline. Genetic and phenotypic data was combined with two independent samples to enable frequency analyses (N=599). Targeted recruitment of individuals with 2q13 CNVs was undertaken via a patient support group, RGCs and the online rare CNV database DECIPHER (N=25). The frequency of pathogenic CNVs was 11%, rising to 13% in the replication cohort. Both novel and recurrent loci were found to harbour pathogenic CNVs, with 70% at established NDD risk loci. A significantly higher population frequency of CNVs was identified in NDD risk regions (10%), compared with schizophrenia (3.1%, p<0.0001) and ID/autism spectrum disorder (6.5%, p<0.0008) populations. Phenotypic characterisation of CNVs at the 2q13 region suggests an early-onset neuropsychiatric phenotype with a high incidence of attention deficit hyperactivity disorder (ADHD) and challenging behaviours. There is a high yield of pathogenic CNVs in patients with co-morbid neurodevelopmental phenotypes. In the main part, distinct loci are not involved in co-morbid NDD risk, but risk arises from the same loci identified in single disorder cohorts. Detailed phenotypic investigation of the 2q13 locus indicates that pleiotropy exists, however there is a preferential psychiatric outcome – in this instance ADHD. Understanding the factors which modulate a CNV region with a high general risk for NDDs to a preferential neuropathological pathway will be key to understanding the complex hierarchy of psychiatric nosology and developing successful therapeutic interventions

This is your brain on the iPad

The proliferative usage of multimedia tools in the classroom reflects an increasingly technocratic education system. Technology provides educators with new opportunities to reach students in innovative ways. We describe the use of iPads and several proprietary applications in a General Psychology course as one opportunity to improve student learning outcomes. Quantitative and qualitative evidence will be provided of the pre- and post-tests, which both show positive significant outcomes

Case-Building Behavior, Persistence, and Emergence Success of \u3ci\u3ePycnopsyche Guttifer\u3c/i\u3e (Walker) (Trichoptera: Limnephilidae) in Laboratory and \u3ci\u3ein situ\u3c/i\u3e Environments: Potential Trade-Offs of Material Preference

When removed from their cases in a non-flow laboratory environment, 5th instar Pycnopsyche guttifer (Walker) larvae were always successful in constructing a new case within 24 h when woody debris was present as a material choice. Most were successful within 1 h. Larvae were never successful at case building in the absence of wood in a non-flow environment. These laboratory-constructed ‘emergency cases’ were flimsy, lacking in shape, and larger than field cases. Laboratory case size, shape, and material preference remained constant after repeated daily evacuations over a series of 10 days. Larvae could be induced to construct a case composed of mineral particles only in the absence of wood and when placed in a laboratory stream with simulated flow conditions, or in situ in a natural stream. The emergence success of P. guttifer specimens induced to build these mineral cases, however, was significantly higher than that of larvae remaining in their field cases or of larvae that built wood cases. This result is likely due to a fungal infection that affected only larvae in wood cases. Our results demonstrate a scenario where a clearly non-preferred case construction material appears to increase survival